Summary

The Research Assistant II will play a key role in coordinating and conducting experiments to explore transcriptional regulation by DNA methylation in development and tumorigenesis. Dr. Shen’s research group employs cutting-edge technologies, including single-cell transcriptomics, epigenomics, and CRISPR-based epigenome editing, to investigate the role of DNA methylation in health and disease.
We are seeking a highly motived team member to support ongoing research projects by performing experiments using animal models and primary cell cultures.

Job Duties

• Design, conduct, analyze, and troubleshoot experiments in molecular and cellular biology, utilizing techniques such as PCR, cloning, DNA/RNA extraction, Westernblot, and cell culture.
• Conduct preclinical animal studies using genetically and epigenetically engineered mouse models.
  • Responsibilities will include breeding and genotyping mice, tracking tumor phenotypes, performing histologic analyses (including immunohistochemistry), and administering intraperitoneal (IP) and tail vein injections.
• Document experimental procedures and results, maintaining accurate and organized records of both written and electronic data, ensuring that all records are easily accessible.
• Supervise and mentor laboratory personnel, including technicians and students, providing training and guidance as needed.

Minimum Qualifications

• Bachelor's degree in a Basic Science or a related field.
• Three years of relevant experience.

Preferred Qualifications

• Master’s degree in natural science or related field.
• At least one year of experience in handling mice.