About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes, and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity, and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds, and experiences to our work -- and that our teams align with the people we serve to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds, and perspectives; this is reflected in our work and represented in our people.

Position Summary

The labs of Drs. Pichiorri and Krishnan in the Department of hematopoietic malignancies translational science and Briskin Myeloma center are looking for a Postdoctoral Fellow. This candidate directs the work of a laboratory or undertakes research projects in collaboration with academic supervisor, making innovative contributions pertaining to laboratory procedures which may not change the course of an investigation but do indicate significant independent contribution. This candidate will consult with the academic supervisor on the scope and plan of approach to a research project; reads abstracts and articles; organize and plan techniques; plan and assign the work of at least one lab staff advising on problems they are unable to solve; contribute original ideas to the laboratory research; standardize new techniques and experimental methodologies; write manuscripts and helps the PI with grant writing.

Specifically for this position experience in medical immunology and in bioinformatics is preferred. The post-doc will support the development of a novel antibody that will work as check point inhibitor in multiple myeloma and leukemia. The post-doc will also support a variety of routine and non-routine laboratory research experiments as well as records and validates results for accuracy and completeness.

Specific experience includes:

· Experienced with sample preparation (A to Z), familiar with MACS Quant instrument and data analysis with FlowJo software.

· Multi-parametric flow analysis

· Cloning experience including CRISPER

· Cell culturing and primary sample preparation

· Experienced with primer design of genes, RNA extraction from tissues and cell lines with Trizol and kits, cDNA synthesis, electrophoresis, Real-time PCR (Corbett, RG-6000)

· Animal handling

Basic education, experience and skills required for consideration:

· PhD or M.D.

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.