Staff Scientist- Organ Chip-Enabled Therapeutics

Harvard Medical School

Boston, MA

Job posting number: #7076588

Posted: March 31, 2021

Application Deadline: Open Until Filled

Job Description

Job Summary

About you:

You are a collaborative, impact-focused problem solver who wants to be part of a dynamic team dedicated to creating and commercializing novel therapeutic capabilities. You want the freedom to explore, to push the boundaries of what is possible, and use your ambition to tackle challenging projects in a fast-paced, industry-focused environment without a lot of administrative hurdles. You enjoy working with diverse groups of people and combining your expertise to create innovations that can change the world. You think differently, you’re adaptable, and others may have called your ideas “weird.” That’s great; we like weird!!

About Us:

The Wyss Institute for Biologically Inspired Engineering at Harvard University is a pathbreaking model for translational research Our mission is to transform healthcare and the environment by emulating the way nature builds, and getting our innovations out of the lab and into the real world, fast. At the Wyss Institute, faculty from premier academic and clinical institutions work in teams composed of staff scientists, postdocs, graduate students, industry experts, business development leaders, and entrepreneurs across disciplines to produce new technologies that don’t just succeed at making it to the market – they disrupt it. We support research that universities, companies, and VC firms don’t fund because they claim it’s too risky. We prefer to use the word “challenging,” and we love challenges. For more information, visit:

About the Role:

We are looking for an innovative Scientist with significant expertise in molecular cell biology and physiology to join our Bioinspired Therapeutics and Diagnostics team. Reporting to the Lead Staff Scientist, you will perform research focusing on the discovery of new disease mechanisms, identification of therapeutic targets, and the discovery, design, and development of novel therapeutic compounds in various conventional culture formats as well as Organ chips. To learn more about our organ-on-chip bioinspired technologies, go to: taxonomy=technology_area&term=99.

Job-Specific Responsibilities

What you’ll do:

Manage sponsored research programs that design and develop therapeutics based on microfluidic organ-on-chip human in vitro experimentation technology.
Lead junior team members on executing grant deliverables
Implement and execute experiments at the bench using in vitro cell based assays, primary cell culture, cell-based microfluidic organ chip assays, and molecular, biochemical and genetic analysis methods.
Analyze data/collaborate on data analysis and visualization using bioinformatic techniques
Design experimental protocols and procedures.
Mentor, supervise and train post-doctoral fellows, graduate students, interns and technicians.
Collaborate with other project platforms and business development teams to help identify and establish commercial opportunities, licensing structures and start up strategies within our therapeutics and diagnostics programs.
Write research proposals, reports, patent applications, presentations and publications, providing critical data, figures, or information for grant and patent submissions.
Work with other team members to establish and manage external collaborations in pursuit of the Institute’s entrepreneurial mission; Services as a point of contact with collaborating laboratories.
Demonstrate a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.
Identify innovative solutions to technical and resource issues to move projects forward
Identify opportunities for collaboration and funding in existing and new disease areas

Basic Qualifications

What you'll need:
Bachelor’s degree in Cell Biology, Physiology, Cancer Biology, Pharmacology or related field required.
5 or more years of experience working in molecular cell biology, physiology or related field. Advanced education may count towards years of experience.

Additional Qualifications and Skills

Desirable Skills:
PhD in Cell Biology, Physiology, Cancer Biology, Pharmacology or related field strongly preferred.
Extensive experience with any of the following disease areas: cancer, lung disease, infectious diseases or gastrointestinal disorders required.
Experience with cancer, stromal-epithelial interactions, blood brain barrier, microvascular cells as well as IPS-derived cells and organoid-based cultures preferred.
Strong organizational and communication skills to assist and collaborate with a multidisciplinary group of technology innovators, engineers, biologist and clinicians.
Demonstrated ability to tackle and lead multiple projects while simultaneously performing bench work as a member of an integrated team is essential

Additional Information

Offer contingent on successful completion of pre-placement medical evaluation.

Why you’ll like working with us:

At the Wyss Institute, you’re a member of a supportive, dynamic community that is united by its shared goal of changing the world through groundbreaking technology development and commercialization. We encourage your professional growth and development through mentorship and tuition reimbursement to support continued learning, and more. We also support your physical, financial, and mental well-being through generous time off benefits, gym reimbursements, and other programs offered through Harvard. We value an inclusive and diverse workforce, and believe that our differences enrich the work environment for all.

Harvard Medical School strives to cultivate an environment that promotes inclusiveness and collaboration among students, faculty and staff and to create new avenues for discussion that will advance our shared mission to improve the health of people throughout the world.

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